Lactobacilli make up the majority of the normal vaginal microflora. Lactobacillus bacteria produce lactic acid and in this way help maintain the normal pH, preventing dysbiosis and protecting against the overgrowth of pathogenic bacteria and fungi, which cause vaginitis and yeast infections respectively. When lactobacilli are taken orally, they pass through the stomach, the small intestine, and the large intestine before reaching the vagina. Their transfer to the vagina occurs through skin contact in the perineal area. In order for sufficient amounts of lactobacilli to reach the female vagina, it is important to take high quantities from the beginning.
The strains Lactobacillus rhamnosus HN001, Lactobacillus acidophilus LA14, Lactobacillus rhamnosus CA15, Lactobacillus crispatus, Lactobacillus gasseri, Lactobacillus jensenii, and Lactobacillus fermentum have been proven to support the vaginal microbiome. Taking L. rhamnosus CA15 leads to significant improvement in clinical signs and symptoms even 30 days after the end of treatment. The L. fermentum strain has been selected for its strong antimicrobial activity. The strains L. crispatus, L. gasseri, and L. jensenii have been chosen due to the dominant presence of these specific lactobacilli species in the vaginal environment of healthy women.
